Fibrinogen concentrate in bleeding patients
نویسندگان
چکیده
منابع مشابه
Bleeding management with fibrinogen concentrate targeting a high-normal plasma fibrinogen level: a pilot study
BACKGROUND Bleeding diathesis after aortic valve operation and ascending aorta replacement (AV-AA) is managed with fresh-frozen plasma (FFP) and platelet concentrates. The aim was to compare haemostatic effects of conventional transfusion management and FIBTEM (thromboelastometry test)-guided fibrinogen concentrate administration. METHODS A blood products transfusion algorithm was developed u...
متن کاملRecovery of fibrinogen after administration of fibrinogen concentrate to patients with severe bleeding after cardiopulmonary bypass surgery
BACKGROUND Normalization of plasma fibrinogen levels may be associated with satisfactory haemostasis and reduced bleeding. The aim of this retrospective study was to assess fibrinogen recovery parameters after administration of fibrinogen concentrate (Haemocomplettan P) to patients with diffuse bleeding in cardiovascular surgery. Data on transfusion and patient outcomes were also collected. M...
متن کاملFibrinogen concentrate substitution therapy in patients with massive haemorrhage and low plasma fibrinogen concentrations.
BACKGROUND Patients experiencing massive haemorrhage are at high risk of developing coagulopathy through loss, consumption, and dilution of coagulation factors and platelets. It has been reported that plasma fibrinogen concentrations may reach a critical low level relatively early during bleeding, calling for replacement fibrinogen therapy. Cryoprecipitate has been widely used in the past, but ...
متن کاملCRITICAL CARE Bleeding management with fibrinogen concentrate targeting a high-normal plasma fibrinogen level: a pilot study
Methods. A blood products transfusion algorithm was developed using retrospective data from 42 elective patients (Group A). Two units of platelet concentrate were transfused after cardiopulmonary bypass, followed by 4 u of FFP if bleeding persisted, if platelet count was 100 10 ml when removing the aortic clamp, and vice versa if platelet count was .100 10 ml. The trigger for each therapy step ...
متن کاملFibrinogen concentrate therapy in complex cardiac surgery.
OBJECTIVES Fibrinogen concentrate increasingly is used to treat coagulopathic bleeding in cardiac surgery although its effectiveness and safety have not been shown. The authors conducted a cohort study to quantify the effects of fibrinogen concentrate on postoperative blood loss and transfusion and the occurrence of adverse clinical events in complex cardiac surgery patients. DESIGN A cohort ...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2013
ISSN: 1465-1858
DOI: 10.1002/14651858.cd008864.pub2